Cavis Wirecath® pressure guide wire
Developed and manufactured in Scandinavia
Our goal when developing the Wirecath was to create a pressure guide wire that consistently delivers accurate measurements. Wirecath is the only pressure wire immune to hydrostatic pressure errors, a proven problem with all traditional pressurewires (1, 2, 3). At the same time it gives you unique torque control for easy navigation, even in the most complex anatomies.
Precision. Quite Simply.


Discover the revolutionary technology

99% of
population
No errors in measurements due to hydrostatic pressure or drift
All traditional sensor-tipped pressure wires are affected by a physical phenomenon causing hydrostatic pressure error (1, 2, 3). The measuring error varies from patient to patient, but the data variation can be significant.
With Wirecath®, the hemodynamic pressure measurements are performed through the fluid-filled interior of the wire, in combination with an external pressure transducer. This is why the Wirecath pressure guide wire is not prone to hydrostatic pressure errors (4, 5) delivering correct, precise measurements.
Moreover, drift is avoided by using the external pressure transducer.

Experience reliable wire performance in tortuous vessels
The torque is transmitted directly to the tip without interference from any inbuilt cables, optical fibers or sensors. The connection rotates freely to the external pressure transducer, to facilitate maximum control and torque response, also in the most complex anatomies. The shapeable and atraumatic soft tip is designed to protect the vessel, without compromising shape retention.

Accurately measure and diagnose
Wirecath® provides accurate and reproducible hemodynamic pressure measurements throughout the entire procedure. The connection of the wire to the transducer is easy to do. After reconnection, the signal is reliable. Pressure measurements remain reliable, also at elevated heart rates.

Cath lab compatibility and easy integration
No additional hardware is needed in your lab. Use the external pressure transducer, and the integrated FFR software of your system to measure physiological indices such as resting Pd/Pa, FFR, and do research in pressure-derived CFR.
Resting ratios
Based on the CONTRAST study data with 627 analysable patients, (1, 3) and the RESOLVE study with 1593 analysable measurements (2), it was shown that Pd/Pa has an excellent correlation with iFR of r = 0.96 and r=0.97, respectively.
When iFR was measured in the same vessel twice, the same correlation of r = 0.96 between repeated measurements was shown (1), see figure below.
Based on the CONTRAST study data, using iFR ≤0.89 as a reference standard, the agreement with Pd/Pa and its best cut-off value were Pd/Pa ≤0.91 (3).
In the RESOLVE study the best cut-off to predict FFR ≤0.80 was iFR ≤0.90 and Pd/Pa ≤0.92 (2).
Outcome
An outcome study showed equal outcome between different resting indices, including Pd/Pa (4).
Guideline
ACC/AATS/AHA/ASE/ASNC/SCAI/SCCT/STS 2017 Appropriate Use Criteria for Coronary Revascularization in Patients With Stable Ischemic Heart Disease (5):
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”Newer physiological measurements that do not require hyperemia measure […] during the whole cardiac cycle or the wave-free portion of the cycle […] have similar diagnostic concordance with FFR […]”
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”Substitution of one of the newer physiological measurements for FFR may be considered provided the appropriate reference values are used”
More
Coronary auto-regulation explains why resting pressure indices, including Pd/Pa, can be used to detect the haemodynamic significance of coronary artery stenoses (6).
FFR, iFR, and Pd/Pa showed a similar performance when compared with PET imaging-derived blood flow (7).
Videos regarding the class effect among resting indices: